JNJ 10191584 maleate
CAS No. 869497-75-6
JNJ 10191584 maleate ( JNJ 10191584 maleate salt; VUF6002 maleate )
Catalog No. M27640 CAS No. 869497-75-6
histamine H4 receptor silent antagonist
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 113 | Get Quote |
|
5MG | 165 | Get Quote |
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10MG | 203 | Get Quote |
|
25MG | 447 | Get Quote |
|
50MG | 651 | Get Quote |
|
100MG | 888 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
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Biological Information
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Product NameJNJ 10191584 maleate
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NoteResearch use only, not for human use.
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Brief Descriptionhistamine H4 receptor silent antagonist
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Descriptionhistamine H4 receptor silent antagonist(In Vitro):JNJ 10191584 maleate shows 540-fold selectivity to H4 receptor(Ki = 14.1 μM).(In Vivo):In spared nerve injury mice, JNJ 10191584 maleate (10 μg/μL; intra locus coeruleus administration) abolishes VUF-induced anti-allodynic effect and prevents the anti-allodynic effect of VUF 8430. JNJ 10191584 maleate (6 μg/mouse; intrathecal administration) prevents VUF 8430-induced anti-allodynic effect.
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SynonymsJNJ 10191584 maleate salt; VUF6002 maleate
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PathwayOthers
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TargetOther Targets
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RecptorDNA/RNA Synthesis
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Research Area——
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Indication——
Chemical Information
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CAS Number869497-75-6
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Formula Weight394.8
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Molecular FormulaC17H19ClN4O5
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Purity>98% (HPLC)
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Solubility——
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SMILESOC(=O)\C=C\C(O)=O.CN1CCN(CC1)C(=O)c1nc2ccc(Cl)cc2[nH]1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Hassan AE, et al. 6-Methylpurine derived sugar modified nucleosides: Synthesis and evaluation of their substrate activity with purine nucleoside phosphorylases. Bioorg Chem. 2016 Apr;65:9-16.
molnova catalog
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