JNJ 10191584 maleate

CAS No. 869497-75-6

JNJ 10191584 maleate ( JNJ 10191584 maleate salt; VUF6002 maleate )

Catalog No. M27640 CAS No. 869497-75-6

histamine H4 receptor silent antagonist

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 113 Get Quote
5MG 165 Get Quote
10MG 203 Get Quote
25MG 447 Get Quote
50MG 651 Get Quote
100MG 888 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    JNJ 10191584 maleate
  • Note
    Research use only, not for human use.
  • Brief Description
    histamine H4 receptor silent antagonist
  • Description
    histamine H4 receptor silent antagonist(In Vitro):JNJ 10191584 maleate shows 540-fold selectivity to H4 receptor(Ki = 14.1 μM).(In Vivo):In spared nerve injury mice, JNJ 10191584 maleate (10 μg/μL; intra locus coeruleus administration) abolishes VUF-induced anti-allodynic effect and prevents the anti-allodynic effect of VUF 8430. JNJ 10191584 maleate (6 μg/mouse; intrathecal administration) prevents VUF 8430-induced anti-allodynic effect.
  • Synonyms
    JNJ 10191584 maleate salt; VUF6002 maleate
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    DNA/RNA Synthesis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    869497-75-6
  • Formula Weight
    394.8
  • Molecular Formula
    C17H19ClN4O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    OC(=O)\C=C\C(O)=O.CN1CCN(CC1)C(=O)c1nc2ccc(Cl)cc2[nH]1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Hassan AE, et al. 6-Methylpurine derived sugar modified nucleosides: Synthesis and evaluation of their substrate activity with purine nucleoside phosphorylases. Bioorg Chem. 2016 Apr;65:9-16.
molnova catalog
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